miR-203 enhances let-7 biogenesis by targeting LIN28B to suppress tumor growth in lung cancer

Human cancers often exhibit increased microRNA (miRNA) biogenesis and global aberrant expression of miRNAs; thus, targeting the miRNA biogenesis pathway represents a novel strategy for cancer therapy. Here, we report that miR-203 enhances the biogenesis of tumor suppressor let-7 in lung cancer by di...

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Detalles Bibliográficos
Autores principales: Zhou, Yong, Liang, Hongwei, Liao, Zhicong, Wang, Yanbo, Hu, Xiuting, Chen, Xi, Xu, Lin, Hu, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316988/
https://www.ncbi.nlm.nih.gov/pubmed/28218277
http://dx.doi.org/10.1038/srep42680

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