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Ubiquitination and dynactin regulate TMEPAI lysosomal trafficking

The transmembrane prostate androgen-induced protein (TMEPAI) has been reported to be elevated in various tumor cells, is localized to the lysosome and promotes lysosome stability. The molecular mechanism of TMEPAI trafficking however to the lysosome is unknown. Here we report that clathrin and CI-M6...

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Detalles Bibliográficos
Autores principales: Luo, Shenheng, Jing, Lei, Zhao, Tian, Li, Yuyin, Liu, Zhenxing, Diao, Aipo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316989/
https://www.ncbi.nlm.nih.gov/pubmed/28218281
http://dx.doi.org/10.1038/srep42668