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Ubiquitination and dynactin regulate TMEPAI lysosomal trafficking
The transmembrane prostate androgen-induced protein (TMEPAI) has been reported to be elevated in various tumor cells, is localized to the lysosome and promotes lysosome stability. The molecular mechanism of TMEPAI trafficking however to the lysosome is unknown. Here we report that clathrin and CI-M6...
Autores principales: | Luo, Shenheng, Jing, Lei, Zhao, Tian, Li, Yuyin, Liu, Zhenxing, Diao, Aipo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316989/ https://www.ncbi.nlm.nih.gov/pubmed/28218281 http://dx.doi.org/10.1038/srep42668 |
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