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Dual Tracer PET Imaging (68Ga-DOTATATE and 18F-FDG) Features in Pulmonary Carcinoid: Correlation with Tumor Proliferation Index

Pulmonary carcinoid tumors are rare group of lung neoplasms representing 1% of all the lung tumors. The typical bronchial carcinoids showed higher and more selective uptake of (68)Ga-DOTATATE than of (18)F-FDG on PET-CT. The Ki-67(MIB-1), a tumor proliferation index is a prognostic marker in neuroen...

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Autores principales: Bhatkar, Dhiraj, Utpat, Ketaki, Basu, Sandip, Joshi, Jyotsna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317069/
https://www.ncbi.nlm.nih.gov/pubmed/28242984
http://dx.doi.org/10.4103/0972-3919.198476
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author Bhatkar, Dhiraj
Utpat, Ketaki
Basu, Sandip
Joshi, Jyotsna M.
author_facet Bhatkar, Dhiraj
Utpat, Ketaki
Basu, Sandip
Joshi, Jyotsna M.
author_sort Bhatkar, Dhiraj
collection PubMed
description Pulmonary carcinoid tumors are rare group of lung neoplasms representing 1% of all the lung tumors. The typical bronchial carcinoids showed higher and more selective uptake of (68)Ga-DOTATATE than of (18)F-FDG on PET-CT. The Ki-67(MIB-1), a tumor proliferation index is a prognostic marker in neuroendocrine tumors for estimating tumor progression. Atypical carcinoids have higher Ki-67 index and have an increased propensity to metastasize as compared to typical ones. (68)Ga-DOTATATE PET imaging along with Ki-67 can be correlated for better management of patients with neuroendocrine tumors. We describe the dual tracer imaging features in a patient of pulmonary carcinoid with avid (68)Ga-DOTATATE and minimal (18)FDG ((18)Flurodeoxyglucose) uptake diagnosed on the basis of imaging and bronchoscopic biopsy and its correlation with tumor proliferation index.
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spelling pubmed-53170692017-02-27 Dual Tracer PET Imaging (68Ga-DOTATATE and 18F-FDG) Features in Pulmonary Carcinoid: Correlation with Tumor Proliferation Index Bhatkar, Dhiraj Utpat, Ketaki Basu, Sandip Joshi, Jyotsna M. Indian J Nucl Med Case Report Pulmonary carcinoid tumors are rare group of lung neoplasms representing 1% of all the lung tumors. The typical bronchial carcinoids showed higher and more selective uptake of (68)Ga-DOTATATE than of (18)F-FDG on PET-CT. The Ki-67(MIB-1), a tumor proliferation index is a prognostic marker in neuroendocrine tumors for estimating tumor progression. Atypical carcinoids have higher Ki-67 index and have an increased propensity to metastasize as compared to typical ones. (68)Ga-DOTATATE PET imaging along with Ki-67 can be correlated for better management of patients with neuroendocrine tumors. We describe the dual tracer imaging features in a patient of pulmonary carcinoid with avid (68)Ga-DOTATATE and minimal (18)FDG ((18)Flurodeoxyglucose) uptake diagnosed on the basis of imaging and bronchoscopic biopsy and its correlation with tumor proliferation index. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5317069/ /pubmed/28242984 http://dx.doi.org/10.4103/0972-3919.198476 Text en Copyright: © 2017 Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Bhatkar, Dhiraj
Utpat, Ketaki
Basu, Sandip
Joshi, Jyotsna M.
Dual Tracer PET Imaging (68Ga-DOTATATE and 18F-FDG) Features in Pulmonary Carcinoid: Correlation with Tumor Proliferation Index
title Dual Tracer PET Imaging (68Ga-DOTATATE and 18F-FDG) Features in Pulmonary Carcinoid: Correlation with Tumor Proliferation Index
title_full Dual Tracer PET Imaging (68Ga-DOTATATE and 18F-FDG) Features in Pulmonary Carcinoid: Correlation with Tumor Proliferation Index
title_fullStr Dual Tracer PET Imaging (68Ga-DOTATATE and 18F-FDG) Features in Pulmonary Carcinoid: Correlation with Tumor Proliferation Index
title_full_unstemmed Dual Tracer PET Imaging (68Ga-DOTATATE and 18F-FDG) Features in Pulmonary Carcinoid: Correlation with Tumor Proliferation Index
title_short Dual Tracer PET Imaging (68Ga-DOTATATE and 18F-FDG) Features in Pulmonary Carcinoid: Correlation with Tumor Proliferation Index
title_sort dual tracer pet imaging (68ga-dotatate and 18f-fdg) features in pulmonary carcinoid: correlation with tumor proliferation index
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317069/
https://www.ncbi.nlm.nih.gov/pubmed/28242984
http://dx.doi.org/10.4103/0972-3919.198476
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