Characteristics and Validation Techniques for PCA-Based Gene-Expression Signatures

Background. Many gene-expression signatures exist for describing the biological state of profiled tumors. Principal Component Analysis (PCA) can be used to summarize a gene signature into a single score. Our hypothesis is that gene signatures can be validated when applied to new datasets, using inhe...

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Detalles Bibliográficos
Autores principales: Berglund, Anders E., Welsh, Eric A., Eschrich, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317117/
https://www.ncbi.nlm.nih.gov/pubmed/28265563
http://dx.doi.org/10.1155/2017/2354564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317117/
https://www.ncbi.nlm.nih.gov/pubmed/28265563
http://dx.doi.org/10.1155/2017/2354564

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