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N-Acetylcysteine Attenuates Diabetic Myocardial Ischemia Reperfusion Injury through Inhibiting Excessive Autophagy

Background. Excessive autophagy is a major mechanism of myocardial ischemia reperfusion injury (I/RI) in diabetes with enhanced oxidative stress. Antioxidant N-acetylcysteine (NAC) reduces myocardial I/RI. It is unknown if inhibition of autophagy may represent a mechanism whereby NAC confers cardiop...

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Detalles Bibliográficos
Autores principales: Wang, Sheng, Wang, Chunyan, Yan, Fuxia, Wang, Tingting, He, Yi, Li, Haobo, Xia, Zhengyuan, Zhang, Zhongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317145/
https://www.ncbi.nlm.nih.gov/pubmed/28265179
http://dx.doi.org/10.1155/2017/9257291

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