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Effects of U0126 and MK2206 on cell growth and re-growth of endometriotic stromal cells grown on substrates of varying stiffness

Endometriosis is a common gynecological disorder responsible for infertility and pelvic pain. A complete cure for patients with endometriosis awaits new targets and strategies. Here we show that U0126 (a MEK inhibitor) and MK2206 (an AKT inhibitor) synergistically inhibit cell growth of deep endomet...

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Detalles Bibliográficos
Autores principales:	Matsuzaki, Sachiko, Pouly, Jean-Luc, Canis, Michel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317159/ https://www.ncbi.nlm.nih.gov/pubmed/28218307 http://dx.doi.org/10.1038/srep42939

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