Structural characterization of EasH (Aspergillus japonicus) – an oxidase involved in cycloclavine biosynthesis

Aj_EasH is a non-heme iron- and α-keto-glutarate-dependent oxidase that is responsible for an unusual cyclopropyl ring formation in the biosynthesis of the fungal ergot alkaloid cycloclavine. The three dimensional structure of Aj_EasH (2.2 Å resolution) reported here provides insight into the mechan...

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Detalles Bibliográficos
Autores principales: Jakubczyk, Dorota, Caputi, Lorenzo, Stevenson, Clare E. M., Lawson, David M., O'Connor, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317212/
https://www.ncbi.nlm.nih.gov/pubmed/27885368
http://dx.doi.org/10.1039/c6cc08438a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317212/
https://www.ncbi.nlm.nih.gov/pubmed/27885368
http://dx.doi.org/10.1039/c6cc08438a

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