Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16

CDK16 (also known as PCTAIRE1 or PCTK1) is an atypical member of the cyclin-dependent kinase (CDK) family that has emerged as a key regulator of neurite outgrowth, vesicle trafficking and cancer cell proliferation. CDK16 is activated through binding to cyclin Y via a phosphorylation-dependent 14-3-3...

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Detalles Bibliográficos
Autores principales: Dixon-Clarke, Sarah E., Shehata, Saifeldin N., Krojer, Tobias, Sharpe, Timothy D., vonDelft, Frank, Sakamoto, Kei, Bullock, Alex N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317395/
https://www.ncbi.nlm.nih.gov/pubmed/28057719
http://dx.doi.org/10.1042/BCJ20160941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317395/
https://www.ncbi.nlm.nih.gov/pubmed/28057719
http://dx.doi.org/10.1042/BCJ20160941

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