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Operon mRNAs are organized into ORF-centric structures that predict translation efficiency

Bacterial mRNAs are organized into operons consisting of discrete open reading frames (ORFs) in a single polycistronic mRNA. Individual ORFs on the mRNA are differentially translated, with rates varying as much as 100-fold. The signals controlling differential translation are poorly understood. Our...

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Detalles Bibliográficos
Autores principales:	Burkhardt, David H, Rouskin, Silvi, Zhang, Yan, Li, Gene-Wei, Weissman, Jonathan S, Gross, Carol A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Computational and Systems Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318159/ https://www.ncbi.nlm.nih.gov/pubmed/28139975 http://dx.doi.org/10.7554/eLife.22037

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