Saliva Versus Plasma Bioequivalence of Azithromycin in Humans: Validation of Class I Drugs of the Salivary Excretion Classification System

AIM: The aim of this study was to compare human pharmacokinetics and bioequivalence metrics in saliva versus plasma for azithromycin as a model class I drug of the Salivary Excretion Classification System (SECS). METHODS: A pilot, open-label, two-way crossover bioequivalence study was done, and invo...

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Detalles Bibliográficos
Autores principales: Idkaidek, Nasir, Arafat, Tawfiq, Hamadi, Hazim, Hamadi, Salim, Al-Adham, Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318338/
https://www.ncbi.nlm.nih.gov/pubmed/28074334
http://dx.doi.org/10.1007/s40268-016-0170-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318338/
https://www.ncbi.nlm.nih.gov/pubmed/28074334
http://dx.doi.org/10.1007/s40268-016-0170-8

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