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Modeling of variability and uncertainty in human health risk assessment

Health risk assessments have been carried out worldwide to examine potential health risk due to exposure to toxic contaminants in various environments. In risk assessment, it is most important to know the nature of all available information, data or model parameters. It is observed that available in...

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Autor principal: Dutta, Palash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318352/
https://www.ncbi.nlm.nih.gov/pubmed/28239562
http://dx.doi.org/10.1016/j.mex.2017.01.005
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author Dutta, Palash
author_facet Dutta, Palash
author_sort Dutta, Palash
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description Health risk assessments have been carried out worldwide to examine potential health risk due to exposure to toxic contaminants in various environments. In risk assessment, it is most important to know the nature of all available information, data or model parameters. It is observed that available information/data are tainted with uncertainty and variability in the same time, i.e., uncertainty and variability co-exist. In such situation it is important to devise method for processing both uncertainty and variability into same framework and which is an open issue. In this regards, this paper presents an algorithm to combined approach to propagate variability and uncertainty in the same framework. The differences and advantages of this algorithm over the existing methods are presented below: • The representation of uncertain model parameters are probabilistic together with generalized fuzzy numbers and normal interval valued fuzzy numbers. • The results obtained are then interpreted in terms of p-box and fuzzy numbers. • The advantage of this approach over the existing methods is that this approach gives an accurate resultant fuzzy number which is of trapezoidal type generalized fuzzy number that is different from the existing methods.
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spelling pubmed-53183522017-02-26 Modeling of variability and uncertainty in human health risk assessment Dutta, Palash MethodsX Method Article Health risk assessments have been carried out worldwide to examine potential health risk due to exposure to toxic contaminants in various environments. In risk assessment, it is most important to know the nature of all available information, data or model parameters. It is observed that available information/data are tainted with uncertainty and variability in the same time, i.e., uncertainty and variability co-exist. In such situation it is important to devise method for processing both uncertainty and variability into same framework and which is an open issue. In this regards, this paper presents an algorithm to combined approach to propagate variability and uncertainty in the same framework. The differences and advantages of this algorithm over the existing methods are presented below: • The representation of uncertain model parameters are probabilistic together with generalized fuzzy numbers and normal interval valued fuzzy numbers. • The results obtained are then interpreted in terms of p-box and fuzzy numbers. • The advantage of this approach over the existing methods is that this approach gives an accurate resultant fuzzy number which is of trapezoidal type generalized fuzzy number that is different from the existing methods. Elsevier 2017-01-31 /pmc/articles/PMC5318352/ /pubmed/28239562 http://dx.doi.org/10.1016/j.mex.2017.01.005 Text en © 2017 Published by Elsevier B.V. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Method Article
Dutta, Palash
Modeling of variability and uncertainty in human health risk assessment
title Modeling of variability and uncertainty in human health risk assessment
title_full Modeling of variability and uncertainty in human health risk assessment
title_fullStr Modeling of variability and uncertainty in human health risk assessment
title_full_unstemmed Modeling of variability and uncertainty in human health risk assessment
title_short Modeling of variability and uncertainty in human health risk assessment
title_sort modeling of variability and uncertainty in human health risk assessment
topic Method Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318352/
https://www.ncbi.nlm.nih.gov/pubmed/28239562
http://dx.doi.org/10.1016/j.mex.2017.01.005
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