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Lack of ABCG2 Leads to Biventricular Dysfunction and Remodeling in Response to Hypoxia
Aims: The ATP-binding cassette (ABC)G2 transporter protects the heart from pressure overload-induced ventricular dysfunction but also protects cancer cells from chemotherapeutic agents. It is upregulated in the myocardium of heart failure patients and clears hypoxia-induced intracellular metabolites...
Autores principales: | Nagy, Bence M., Nagaraj, Chandran, Egemnazarov, Bakytbek, Kwapiszewska, Grazyna, Stauber, Rudolf E., Avian, Alexander, Olschewski, Horst, Olschewski, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318436/ https://www.ncbi.nlm.nih.gov/pubmed/28270772 http://dx.doi.org/10.3389/fphys.2017.00098 |
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