Genomic analysis of a Streptococcus pyogenes strain causing endocarditis in a child

We sequenced the genome of Streptococcus pyogenes strain G773 that caused an infective endocarditis in a 4-year-old boy suffering from acute endocarditis. The 1.9-Mb genome exhibited a specific combination of virulence factors including a complete integrative and conjugative element, sp2905, previou...

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Autores principales: Beye, M., El Karkouri, K., Labas, N., Raoult, D., Fournier, P.-E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Taxonogenomics: Genome of a New Organism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318540/
https://www.ncbi.nlm.nih.gov/pubmed/28239478
http://dx.doi.org/10.1016/j.nmni.2017.01.007
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author Beye, M.
El Karkouri, K.
Labas, N.
Raoult, D.
Fournier, P.-E.
author_facet Beye, M.
El Karkouri, K.
Labas, N.
Raoult, D.
Fournier, P.-E.
author_sort Beye, M.
collection PubMed
description We sequenced the genome of Streptococcus pyogenes strain G773 that caused an infective endocarditis in a 4-year-old boy suffering from acute endocarditis. The 1.9-Mb genome exhibited a specific combination of virulence factors including a complete integrative and conjugative element, sp2905, previously described as incomplete in S. pyogenes, and five bacteriocin-coding genes. However, strain G773 lacked a CRISPR-Cas system.
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spelling pubmed-53185402017-02-26 Genomic analysis of a Streptococcus pyogenes strain causing endocarditis in a child Beye, M. El Karkouri, K. Labas, N. Raoult, D. Fournier, P.-E. New Microbes New Infect Taxonogenomics: Genome of a New Organism We sequenced the genome of Streptococcus pyogenes strain G773 that caused an infective endocarditis in a 4-year-old boy suffering from acute endocarditis. The 1.9-Mb genome exhibited a specific combination of virulence factors including a complete integrative and conjugative element, sp2905, previously described as incomplete in S. pyogenes, and five bacteriocin-coding genes. However, strain G773 lacked a CRISPR-Cas system. Elsevier 2017-01-28 /pmc/articles/PMC5318540/ /pubmed/28239478 http://dx.doi.org/10.1016/j.nmni.2017.01.007 Text en © 2017 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Taxonogenomics: Genome of a New Organism
Beye, M.
El Karkouri, K.
Labas, N.
Raoult, D.
Fournier, P.-E.
Genomic analysis of a Streptococcus pyogenes strain causing endocarditis in a child
title Genomic analysis of a Streptococcus pyogenes strain causing endocarditis in a child
title_full Genomic analysis of a Streptococcus pyogenes strain causing endocarditis in a child
title_fullStr Genomic analysis of a Streptococcus pyogenes strain causing endocarditis in a child
title_full_unstemmed Genomic analysis of a Streptococcus pyogenes strain causing endocarditis in a child
title_short Genomic analysis of a Streptococcus pyogenes strain causing endocarditis in a child
title_sort genomic analysis of a streptococcus pyogenes strain causing endocarditis in a child
topic Taxonogenomics: Genome of a New Organism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318540/
https://www.ncbi.nlm.nih.gov/pubmed/28239478
http://dx.doi.org/10.1016/j.nmni.2017.01.007
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