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Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates

Here, we characterize a subset of ILC3s that express Neuropilin1 (NRP1) and are present in lymphoid tissues, but not in the peripheral blood or skin. NRP1(+) group 3 innate lymphoid cells (ILC3s) display in vitro lymphoid tissue inducer (LTi) activity. In agreement with this, NRP1(+) ILC3s are mainl...

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Detalles Bibliográficos
Autores principales: Shikhagaie, Medya Mara, Björklund, Åsa K., Mjösberg, Jenny, Erjefält, Jonas S., Cornelissen, Anne S., Ros, Xavier Romero, Bal, Suzanne M., Koning, Jasper J., Mebius, Reina E., Mori, Michiko, Bruchard, Melanie, Blom, Bianca, Spits, Hergen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318658/
https://www.ncbi.nlm.nih.gov/pubmed/28199847
http://dx.doi.org/10.1016/j.celrep.2017.01.063