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Effect of prolyl hydroxylase domain 2 haplodeficiency on liver progenitor cell characteristics in early mouse hepatocarcinogenesis

Activation of the hypoxia-inducible factor (HIF)-pathway in hepatocellular carcinoma (HCC) induces therapy resistant tumours, characterized by increased liver progenitor cell (LPCs) characteristics and poor prognosis. We previously reported corresponding results in mice with HCC in which hypoxia was...

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Detalles Bibliográficos
Autores principales:	Bogaerts, Eliene, Paridaens, Annelies, Verhelst, Xavier, Carmeliet, Peter, Geerts, Anja, Van Vlierberghe, Hans, Devisscher, Lindsey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Leibniz Research Centre for Working Environment and Human Factors 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318796/ https://www.ncbi.nlm.nih.gov/pubmed/28337100 http://dx.doi.org/10.17179/excli2016-607

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