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Notch1-promoted TRPA1 expression in erythroleukemic cells suppresses erythroid but enhances megakaryocyte differentiation
The Notch1 pathway plays important roles in modulating erythroid and megakaryocyte differentiation. To screen the Notch1-related genes that regulate differentiation fate of K562 and HEL cells, the expression of transient receptor potential ankyrin 1 (TRPA1) was induced by Notch1 receptor intracellul...
Autores principales: | Chen, Ji-Lin, Ping, Yueh-Hsin, Tseng, Min-Jen, Chang, Yuan-I, Lee, Hsin-Chen, Hsieh, Rong-Hong, Yeh, Tien-Shun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318885/ https://www.ncbi.nlm.nih.gov/pubmed/28220825 http://dx.doi.org/10.1038/srep42883 |
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