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Parenteral administration of factor Xa/IIa inhibitors limits experimental aortic aneurysm and atherosclerosis

Intraluminal thrombus is a consistent feature of human abdominal aortic aneurysm (AAA). Coagulation factor Xa (FXa) catalyses FII to thrombin (FIIa). We examined the effect of FXa/FIIa inhibition on experimental aortic aneurysm in apolipoprotein E-deficient (ApoE(−/−)) mice infused with angiotensin...

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Detalles Bibliográficos
Autores principales:	Moran, Corey S., Seto, Sai-Wang, Krishna, Smriti M., Sharma, Surabhi, Jose, Roby J., Biros, Erik, Wang, Yutang, Morton, Susan K., Golledge, Jonathan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318894/ https://www.ncbi.nlm.nih.gov/pubmed/28220880 http://dx.doi.org/10.1038/srep43079

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