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Pan-neurexin perturbation results in compromised synapse stability and a reduction in readily releasable synaptic vesicle pool size

Neurexins are a diverse family of cell adhesion molecules that localize to presynaptic specializations of CNS neurons. Heterologous expression of neurexins in non-neuronal cells leads to the recruitment of postsynaptic proteins in contacting dendrites of co-cultured neurons, implicating neurexins in...

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Detalles Bibliográficos
Autores principales: Quinn, Dylan P., Kolar, Annette, Wigerius, Michael, Gomm-Kolisko, Rachel N., Atwi, Hanine, Fawcett, James P., Krueger, Stefan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318902/
https://www.ncbi.nlm.nih.gov/pubmed/28220838
http://dx.doi.org/10.1038/srep42920

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