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Pan-neurexin perturbation results in compromised synapse stability and a reduction in readily releasable synaptic vesicle pool size
Neurexins are a diverse family of cell adhesion molecules that localize to presynaptic specializations of CNS neurons. Heterologous expression of neurexins in non-neuronal cells leads to the recruitment of postsynaptic proteins in contacting dendrites of co-cultured neurons, implicating neurexins in...
Autores principales: | Quinn, Dylan P., Kolar, Annette, Wigerius, Michael, Gomm-Kolisko, Rachel N., Atwi, Hanine, Fawcett, James P., Krueger, Stefan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318902/ https://www.ncbi.nlm.nih.gov/pubmed/28220838 http://dx.doi.org/10.1038/srep42920 |
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