TWIST1 induces MMP3 expression through up-regulating DNA hydroxymethylation and promotes catabolic responses in human chondrocytes

The objective was to investigate the levels of TWIST1 in normal and OA cartilage and examine its role in regulating gene expression in chondrocytes. Human cartilage tissues and chondrocytes were obtained at autopsy from normal knee joints and from OA-affected joints at the time of total knee arthrop...

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Detalles Bibliográficos
Autores principales: Hasei, Joe, Teramura, Takeshi, Takehara, Toshiyuki, Onodera, Yuta, Horii, Takuro, Olmer, Merissa, Hatada, Izuho, Fukuda, Kanji, Ozaki, Toshifumi, Lotz, Martin K., Asahara, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318945/
https://www.ncbi.nlm.nih.gov/pubmed/28220902
http://dx.doi.org/10.1038/srep42990

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