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Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model

BACKGROUND: The prognosis of triple-negative breast cancer (TNBC) is still difficult to establish. Some TNBC benefit from radiotherapy (RT) and are cured, while in other patients metastases appear during the first 3 years after treatment. In this study, an animal model of TNBC was used to determine...

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Detalles Bibliográficos
Autores principales: Bouchard, Gina, Therriault, Hélène, Geha, Sameh, Bujold, Rachel, Saucier, Caroline, Paquette, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318978/
https://www.ncbi.nlm.nih.gov/pubmed/28103615
http://dx.doi.org/10.1038/bjc.2016.448