Cargando…
Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model
BACKGROUND: The prognosis of triple-negative breast cancer (TNBC) is still difficult to establish. Some TNBC benefit from radiotherapy (RT) and are cured, while in other patients metastases appear during the first 3 years after treatment. In this study, an animal model of TNBC was used to determine...
Autores principales: | Bouchard, Gina, Therriault, Hélène, Geha, Sameh, Bujold, Rachel, Saucier, Caroline, Paquette, Benoit |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318978/ https://www.ncbi.nlm.nih.gov/pubmed/28103615 http://dx.doi.org/10.1038/bjc.2016.448 |
Ejemplares similares
-
Stimulation of triple negative breast cancer cell migration and metastases formation is prevented by chloroquine in a pre-irradiated mouse model
por: Bouchard, Gina, et al.
Publicado: (2016) -
Radiation-enhancement of MDA-MB-231 breast cancer cell invasion prevented by a cyclooxygenase-2 inhibitor
por: Paquette, B, et al.
Publicado: (2011) -
MT4-MMP and EGFR expression levels are key biomarkers for breast cancer patient response to chemotherapy and erlotinib
por: Yip, Cassandre, et al.
Publicado: (2017) -
MT1-MMP is the critical determinant of matrix degradation and invasion by ovarian cancer cells
por: Sodek, K L, et al.
Publicado: (2007) -
In vitro irradiation of basement membrane enhances the invasiveness of breast cancer cells
por: Paquette, B, et al.
Publicado: (2007)