Interaction between HCMV pUL83 and human AIM2 disrupts the activation of the AIM2 inflammasome

BACKGROUND: AIM2, a cytosolic DNA sensor, plays an important role during infection caused by pathogens with double-stranded DNA; however, its role in human cytomegalovirus (HCMV) infection remains unclear. Previously, we showed an increase in AIM2 protein levels during the early stage of HCMV infect...

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Detalles Bibliográficos
Autores principales: Huang, Yuan, Ma, Di, Huang, Heyu, Lu, Yuanyuan, Liao, Yi, Liu, Lingling, Liu, Xinglou, Fang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319029/
https://www.ncbi.nlm.nih.gov/pubmed/28219398
http://dx.doi.org/10.1186/s12985-016-0673-5

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