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Generation of donor-specific Tr1 cells to be used after kidney transplantation and definition of the timing of their in vivo infusion in the presence of immunosuppression

BACKGROUND: Operational tolerance is an alternative to lifelong immunosuppression after transplantation. One strategy to achieve tolerance is by T regulatory cells. Safety and feasibility of a T regulatory type 1 (Tr1)-cell—based therapy to prevent graft versus host disease in patients with hematolo...

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Detalles Bibliográficos
Autores principales:	Mfarrej, Bechara, Tresoldi, Eleonora, Stabilini, Angela, Paganelli, Alessia, Caldara, Rossana, Secchi, Antonio, Battaglia, Manuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319067/ https://www.ncbi.nlm.nih.gov/pubmed/28222739 http://dx.doi.org/10.1186/s12967-017-1133-8

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