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The reversal effect of prothrombin complex concentrate (PCC), activated PCC and recombinant activated factor VII against anticoagulation of Xa inhibitor
BACKGROUND: An increasing number of patients are treated with direct-acting oral anticoagulants (DOACs), but the optimal way to reverse the anticoagulant effect is not known. Specific antidotes are not available and prothrombin complex concentrate (PCC), activated PCC (aPCC) and recombinant factor V...
Autores principales: | Schultz, Nina Haagenrud, Tran, Hoa Thi Tuyet, Bjørnsen, Stine, Henriksson, Carola Elisabeth, Sandset, Per Morten, Holme, Pål Andre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319105/ https://www.ncbi.nlm.nih.gov/pubmed/28239301 http://dx.doi.org/10.1186/s12959-017-0129-1 |
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