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A fresh look at bioresorbable scaffold technology: Intuition pumps
Bioresorbable scaffolds (BRS) are a new enticing treatment option in coronary interventions. Absorb BVS™ Is the most widely used and researched polymer based BRS, eluting everolimus. However currently it has several technical limitations; low radial support, larger strut size, poor visualization, po...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319118/ https://www.ncbi.nlm.nih.gov/pubmed/28228292 http://dx.doi.org/10.1016/j.ihj.2017.01.006 |
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author | Mishra, Sundeep |
author_facet | Mishra, Sundeep |
author_sort | Mishra, Sundeep |
collection | PubMed |
description | Bioresorbable scaffolds (BRS) are a new enticing treatment option in coronary interventions. Absorb BVS™ Is the most widely used and researched polymer based BRS, eluting everolimus. However currently it has several technical limitations; low radial support, larger strut size, poor visualization, poor deliverability and complex implantation technique. Magnesium based BRS are an alternate but they are also limited not only by lower radial support and poor visualization but also earlier bio-absorption. Material processing: blow-molding, annealing, polymer orientation, change in composition and use of higher molecular weight polymer, as well new polymers like tyrosine or salicyclate analogs and even hybrid (polymer and metallic) combined with intelligent cell design has led to evolution of BRS technology. Newer BRS has higher radial strength, lower strut thickness, improved visualization, ease of scaffold implantation as also optimal bio-resorption time. |
format | Online Article Text |
id | pubmed-5319118 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-53191182018-01-01 A fresh look at bioresorbable scaffold technology: Intuition pumps Mishra, Sundeep Indian Heart J Editorial Bioresorbable scaffolds (BRS) are a new enticing treatment option in coronary interventions. Absorb BVS™ Is the most widely used and researched polymer based BRS, eluting everolimus. However currently it has several technical limitations; low radial support, larger strut size, poor visualization, poor deliverability and complex implantation technique. Magnesium based BRS are an alternate but they are also limited not only by lower radial support and poor visualization but also earlier bio-absorption. Material processing: blow-molding, annealing, polymer orientation, change in composition and use of higher molecular weight polymer, as well new polymers like tyrosine or salicyclate analogs and even hybrid (polymer and metallic) combined with intelligent cell design has led to evolution of BRS technology. Newer BRS has higher radial strength, lower strut thickness, improved visualization, ease of scaffold implantation as also optimal bio-resorption time. Elsevier 2017 2017-01-31 /pmc/articles/PMC5319118/ /pubmed/28228292 http://dx.doi.org/10.1016/j.ihj.2017.01.006 Text en © 2017 Cardiological Society of India. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Editorial Mishra, Sundeep A fresh look at bioresorbable scaffold technology: Intuition pumps |
title | A fresh look at bioresorbable scaffold technology: Intuition pumps |
title_full | A fresh look at bioresorbable scaffold technology: Intuition pumps |
title_fullStr | A fresh look at bioresorbable scaffold technology: Intuition pumps |
title_full_unstemmed | A fresh look at bioresorbable scaffold technology: Intuition pumps |
title_short | A fresh look at bioresorbable scaffold technology: Intuition pumps |
title_sort | fresh look at bioresorbable scaffold technology: intuition pumps |
topic | Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319118/ https://www.ncbi.nlm.nih.gov/pubmed/28228292 http://dx.doi.org/10.1016/j.ihj.2017.01.006 |
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