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A fresh look at bioresorbable scaffold technology: Intuition pumps

Bioresorbable scaffolds (BRS) are a new enticing treatment option in coronary interventions. Absorb BVS™ Is the most widely used and researched polymer based BRS, eluting everolimus. However currently it has several technical limitations; low radial support, larger strut size, poor visualization, po...

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Detalles Bibliográficos
Autor principal: Mishra, Sundeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319118/
https://www.ncbi.nlm.nih.gov/pubmed/28228292
http://dx.doi.org/10.1016/j.ihj.2017.01.006
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author Mishra, Sundeep
author_facet Mishra, Sundeep
author_sort Mishra, Sundeep
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description Bioresorbable scaffolds (BRS) are a new enticing treatment option in coronary interventions. Absorb BVS™ Is the most widely used and researched polymer based BRS, eluting everolimus. However currently it has several technical limitations; low radial support, larger strut size, poor visualization, poor deliverability and complex implantation technique. Magnesium based BRS are an alternate but they are also limited not only by lower radial support and poor visualization but also earlier bio-absorption. Material processing: blow-molding, annealing, polymer orientation, change in composition and use of higher molecular weight polymer, as well new polymers like tyrosine or salicyclate analogs and even hybrid (polymer and metallic) combined with intelligent cell design has led to evolution of BRS technology. Newer BRS has higher radial strength, lower strut thickness, improved visualization, ease of scaffold implantation as also optimal bio-resorption time.
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spelling pubmed-53191182018-01-01 A fresh look at bioresorbable scaffold technology: Intuition pumps Mishra, Sundeep Indian Heart J Editorial Bioresorbable scaffolds (BRS) are a new enticing treatment option in coronary interventions. Absorb BVS™ Is the most widely used and researched polymer based BRS, eluting everolimus. However currently it has several technical limitations; low radial support, larger strut size, poor visualization, poor deliverability and complex implantation technique. Magnesium based BRS are an alternate but they are also limited not only by lower radial support and poor visualization but also earlier bio-absorption. Material processing: blow-molding, annealing, polymer orientation, change in composition and use of higher molecular weight polymer, as well new polymers like tyrosine or salicyclate analogs and even hybrid (polymer and metallic) combined with intelligent cell design has led to evolution of BRS technology. Newer BRS has higher radial strength, lower strut thickness, improved visualization, ease of scaffold implantation as also optimal bio-resorption time. Elsevier 2017 2017-01-31 /pmc/articles/PMC5319118/ /pubmed/28228292 http://dx.doi.org/10.1016/j.ihj.2017.01.006 Text en © 2017 Cardiological Society of India. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Editorial
Mishra, Sundeep
A fresh look at bioresorbable scaffold technology: Intuition pumps
title A fresh look at bioresorbable scaffold technology: Intuition pumps
title_full A fresh look at bioresorbable scaffold technology: Intuition pumps
title_fullStr A fresh look at bioresorbable scaffold technology: Intuition pumps
title_full_unstemmed A fresh look at bioresorbable scaffold technology: Intuition pumps
title_short A fresh look at bioresorbable scaffold technology: Intuition pumps
title_sort fresh look at bioresorbable scaffold technology: intuition pumps
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319118/
https://www.ncbi.nlm.nih.gov/pubmed/28228292
http://dx.doi.org/10.1016/j.ihj.2017.01.006
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