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Distribution based nearest neighbor imputation for truncated high dimensional data with applications to pre-clinical and clinical metabolomics studies
BACKGROUND: High throughput metabolomics makes it possible to measure the relative abundances of numerous metabolites in biological samples, which is useful to many areas of biomedical research. However, missing values (MVs) in metabolomics datasets are common and can arise due to both technical and...
Autores principales: | Shah, Jasmit S., Rai, Shesh N., DeFilippis, Andrew P., Hill, Bradford G., Bhatnagar, Aruni, Brock, Guy N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319174/ https://www.ncbi.nlm.nih.gov/pubmed/28219348 http://dx.doi.org/10.1186/s12859-017-1547-6 |
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