Retinoic acid promotes expression of germline-specific genes in chicken blastoderm cells by stimulating Smad1/5 phosphorylation in a feeder-free culture system

BACKGROUND: Producing transgenic chickens with chicken blastodermal cells (cBCs) is inefficient due to the extremely low germline transmission capacity of cBCs. As chicken primordial germ cells (PGCs) have been reported as an efficient method for producing transgenic chickens, the inefficiency of cB...

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Detalles Bibliográficos
Autores principales: Tang, Xiaochuan, Xu, Shiyong, Zhang, Hongpeng, Chen, Qing, Li, Rongyang, Wu, Wangjun, Yu, Minli, Liu, Honglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319176/
https://www.ncbi.nlm.nih.gov/pubmed/28219352
http://dx.doi.org/10.1186/s12896-017-0332-y

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