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Influence of sleep disorders on somatic symptoms, mental health, and quality of life in patients with chronic constipation
BACKGROUND: Sleep disturbance is a common symptom in CC patients, and it is positively related to greater somatic and psychiatric symptoms. METHODS: The participants were 126 adult outpatients with CC. The measures were: constipation—Constipation Scoring System (CSS) and Patient Assessment of Consti...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319508/ https://www.ncbi.nlm.nih.gov/pubmed/28207519 http://dx.doi.org/10.1097/MD.0000000000006093 |
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author | Jiang, Ya Tang, Yu-Rong Xie, Chen Yu, Ting Xiong, Wen-Jie Lin, Lin |
author_facet | Jiang, Ya Tang, Yu-Rong Xie, Chen Yu, Ting Xiong, Wen-Jie Lin, Lin |
author_sort | Jiang, Ya |
collection | PubMed |
description | BACKGROUND: Sleep disturbance is a common symptom in CC patients, and it is positively related to greater somatic and psychiatric symptoms. METHODS: The participants were 126 adult outpatients with CC. The measures were: constipation—Constipation Scoring System (CSS) and Patient Assessment of Constipation-Symptoms (PAC-SYM); sleep—Pittsburgh Sleep Quality Index (PSQI); anxiety—General Anxiety Disorder-7 (GAD-7); depression—Patient Health Questionnaire-9 (PHQ-9); and QOL—Patient Assessment of Constipation Quality of Life (PAC-QOL) and SF-36. Patients were divided into sleep-disorder and normal-sleep groups by their PSQI scores. RESULTS: The sleep-disorder group had significantly higher rates of incomplete defecation and blockage and higher CSS scores, PAC-SYM total scores, and PAC-SYM rectal-item scores than the normal-sleep group. GAD-7 and PHQ-9 scores were significantly higher in patients with poor sleep. Furthermore, sleep disorders, depression, and anxiety were all positively correlated with constipation severity. “Worry/anxiety” score of PAC-QOL scale was significantly higher and scores for seven SF-36 subscales were significantly lower in patients with poor sleep. In addition, correlation analyses showed significant negative relations between QOL and constipation, sleep disturbance, anxiety as well as depression. However, multiple regression revealed that PAC-QOL was positively associated with severe constipation and SF-36 was negatively associated with anxiety and depression. But sleep disturbance was not the independent risk factor for QOL of CC patients. CONCLUSION: Sleep disorders may worsen the physical- and mental health of CC patients. Sleep disturbance may lower CC patients’ QOL indirectly through the combined effects of anxiety, depression, and constipation. |
format | Online Article Text |
id | pubmed-5319508 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-53195082017-03-02 Influence of sleep disorders on somatic symptoms, mental health, and quality of life in patients with chronic constipation Jiang, Ya Tang, Yu-Rong Xie, Chen Yu, Ting Xiong, Wen-Jie Lin, Lin Medicine (Baltimore) 4500 BACKGROUND: Sleep disturbance is a common symptom in CC patients, and it is positively related to greater somatic and psychiatric symptoms. METHODS: The participants were 126 adult outpatients with CC. The measures were: constipation—Constipation Scoring System (CSS) and Patient Assessment of Constipation-Symptoms (PAC-SYM); sleep—Pittsburgh Sleep Quality Index (PSQI); anxiety—General Anxiety Disorder-7 (GAD-7); depression—Patient Health Questionnaire-9 (PHQ-9); and QOL—Patient Assessment of Constipation Quality of Life (PAC-QOL) and SF-36. Patients were divided into sleep-disorder and normal-sleep groups by their PSQI scores. RESULTS: The sleep-disorder group had significantly higher rates of incomplete defecation and blockage and higher CSS scores, PAC-SYM total scores, and PAC-SYM rectal-item scores than the normal-sleep group. GAD-7 and PHQ-9 scores were significantly higher in patients with poor sleep. Furthermore, sleep disorders, depression, and anxiety were all positively correlated with constipation severity. “Worry/anxiety” score of PAC-QOL scale was significantly higher and scores for seven SF-36 subscales were significantly lower in patients with poor sleep. In addition, correlation analyses showed significant negative relations between QOL and constipation, sleep disturbance, anxiety as well as depression. However, multiple regression revealed that PAC-QOL was positively associated with severe constipation and SF-36 was negatively associated with anxiety and depression. But sleep disturbance was not the independent risk factor for QOL of CC patients. CONCLUSION: Sleep disorders may worsen the physical- and mental health of CC patients. Sleep disturbance may lower CC patients’ QOL indirectly through the combined effects of anxiety, depression, and constipation. Wolters Kluwer Health 2017-02-17 /pmc/articles/PMC5319508/ /pubmed/28207519 http://dx.doi.org/10.1097/MD.0000000000006093 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 |
spellingShingle | 4500 Jiang, Ya Tang, Yu-Rong Xie, Chen Yu, Ting Xiong, Wen-Jie Lin, Lin Influence of sleep disorders on somatic symptoms, mental health, and quality of life in patients with chronic constipation |
title | Influence of sleep disorders on somatic symptoms, mental health, and quality of life in patients with chronic constipation |
title_full | Influence of sleep disorders on somatic symptoms, mental health, and quality of life in patients with chronic constipation |
title_fullStr | Influence of sleep disorders on somatic symptoms, mental health, and quality of life in patients with chronic constipation |
title_full_unstemmed | Influence of sleep disorders on somatic symptoms, mental health, and quality of life in patients with chronic constipation |
title_short | Influence of sleep disorders on somatic symptoms, mental health, and quality of life in patients with chronic constipation |
title_sort | influence of sleep disorders on somatic symptoms, mental health, and quality of life in patients with chronic constipation |
topic | 4500 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319508/ https://www.ncbi.nlm.nih.gov/pubmed/28207519 http://dx.doi.org/10.1097/MD.0000000000006093 |
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