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Interacting network of Hippo, Wnt/β-catenin and Notch signaling represses liver tumor formation

Acquiring a selective growth advantage by breaking the proliferation barrier established by gatekeeper genes is a centrally important event in tumor formation. Removal of the mammalian Hippo kinase Mst1 and Mst2 in hepatocytes leads to rapid hepatocellular carcinoma (HCC) formation, indicating that...

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Detalles Bibliográficos
Autores principales:	Kim, Wantae, Khan, Sanjoy Kumar, Yang, Yingzi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2017
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319656/ https://www.ncbi.nlm.nih.gov/pubmed/27881216 http://dx.doi.org/10.5483/BMBRep.2017.50.1.196

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