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Impaired phagocytosis of apoptotic cells causes accumulation of bone marrow-derived macrophages in aged mice

Accumulation of tissue macrophages is a significant characteristic of disease-associated chronic inflammation, and facilitates the progression of disease pathology. However, the functional roles of these bone marrow-derived macrophages (BMDMs) in aging are unclear. Here, we identified age-dependent...

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Detalles Bibliográficos
Autores principales: Kim, Ok-Hee, Kim, Hyojung, Kang, Jinku, Yang, Dongki, Kang, Yu-Hoi, Lee, Dae Ho, Cheon, Gi Jeong, Park, Sang Chul, Oh, Byung-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319664/
https://www.ncbi.nlm.nih.gov/pubmed/27866511
http://dx.doi.org/10.5483/BMBRep.2017.50.1.167