GLM-based optimization of NGS data analysis: A case study of Roche 454, Ion Torrent PGM and Illumina NextSeq sequencing data

BACKGROUND: There are various next-generation sequencing techniques, all of them striving to replace Sanger sequencing as the gold standard. However, false positive calls of single nucleotide variants and especially indels are a widely known problem of basically all sequencing platforms. METHODS: We...

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Detalles Bibliográficos
Autores principales: Sandmann, Sarah, de Graaf, Aniek O., van der Reijden, Bert A., Jansen, Joop H., Dugas, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319672/
https://www.ncbi.nlm.nih.gov/pubmed/28222155
http://dx.doi.org/10.1371/journal.pone.0171983

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