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The desert gerbil Psammomys obesus as a model for metformin-sensitive nutritional type 2 diabetes to protect hepatocellular metabolic damage: Impact of mitochondrial redox state
INTRODUCTION: While metformin (MET) is the most widely prescribed antidiabetic drug worldwide, its beneficial effects in Psammomys obesus (P. obesus), a rodent model that mimics most of the metabolic features of human diabetes, have not been explored thoroughly. Here, we sought to investigate whethe...
Autores principales: | Gouaref, Inès, Detaille, Dominique, Wiernsperger, Nicolas, Khan, Naim Akhtar, Leverve, Xavier, Koceir, Elhadj-Ahmed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319739/ https://www.ncbi.nlm.nih.gov/pubmed/28222147 http://dx.doi.org/10.1371/journal.pone.0172053 |
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