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RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling

OBJECTIVE: Epidermal stem cells (ESCs) play a critical role in wound healing, but the mechanism underlying ESC proliferation is not well defined. Here, we explore the effects of RhoA on ESC proliferation and the possible underlying mechanism. METHODS: Human ESCs were enriched by rapid adhesion to co...

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Detalles Bibliográficos
Autores principales: Wang, Fan, Zhan, Rixing, Chen, Liang, Dai, Xia, Wang, Wenping, Guo, Rui, Li, Xiaoge, Li, Zhe, Wang, Liang, Huang, Shupeng, Shen, Jie, Li, Shirong, Cao, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319766/
https://www.ncbi.nlm.nih.gov/pubmed/28222172
http://dx.doi.org/10.1371/journal.pone.0172613