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A high throughput mutagenic analysis of yeast sumo structure and function

Sumoylation regulates a wide range of essential cellular functions through diverse mechanisms that remain to be fully understood. Using S. cerevisiae, a model organism with a single essential SUMO gene (SMT3), we developed a library of >250 mutant strains with single or multiple amino acid substi...

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Detalles Bibliográficos
Autores principales:	Newman, Heather A., Meluh, Pamela B., Lu, Jian, Vidal, Jeremy, Carson, Caryn, Lagesse, Elizabeth, Gray, Jeffrey J., Boeke, Jef D., Matunis, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319795/ https://www.ncbi.nlm.nih.gov/pubmed/28166236 http://dx.doi.org/10.1371/journal.pgen.1006612

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