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Ribosomal mutations promote the evolution of antibiotic resistance in a multidrug environment

Antibiotic resistance arising via chromosomal mutations is typically specific to a particular antibiotic or class of antibiotics. We have identified mutations in genes encoding ribosomal components in Mycobacterium smegmatis that confer resistance to several structurally and mechanistically unrelate...

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Detalles Bibliográficos
Autores principales:	Gomez, James E, Kaufmann-Malaga, Benjamin B, Wivagg, Carl N, Kim, Peter B, Silvis, Melanie R, Renedo, Nikolai, Ioerger, Thomas R, Ahmad, Rushdy, Livny, Jonathan, Fishbein, Skye, Sacchettini, James C, Carr, Steven A, Hung, Deborah T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Genomics and Evolutionary Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319836/ https://www.ncbi.nlm.nih.gov/pubmed/28220755 http://dx.doi.org/10.7554/eLife.20420

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