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P450(BM3) fused to phosphite dehydrogenase allows phosphite-driven selective oxidations

To facilitate the wider application of the NADPH-dependent P450(BM3,) we fused the monooxygenase with a phosphite dehydrogenase (PTDH). The resulting monooxygenase-dehydrogenase fusion enzyme acts as a self-sufficient bifunctional catalyst, accepting phosphite as a cheap electron donor for the regen...

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Detalles Bibliográficos
Autores principales: Beyer, Nina, Kulig, Justyna K., Bartsch, Anette, Hayes, Martin A., Janssen, Dick B., Fraaije, Marco W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320008/
https://www.ncbi.nlm.nih.gov/pubmed/27900443
http://dx.doi.org/10.1007/s00253-016-7993-7

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