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Growth Arrest-Specific 6 Enhances the Suppressive Function of CD4(+)CD25(+) Regulatory T Cells Mainly through Axl Receptor

Background. Growth arrest-specific (Gas) 6 is one of the endogenous ligands of TAM receptors (Tyro3, Axl, and Mertk), and its role as an immune modulator has been recently emphasized. Naturally occurring CD4(+)CD25(+) regulatory T cells (Tregs) are essential for the active suppression of autoimmunit...

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Detalles Bibliográficos
Autores principales: Zhao, Guang-ju, Zheng, Jia-yi, Bian, Jia-lan, Chen, Long-wang, Dong, Ning, Yu, Yan, Hong, Guang-liang, Chandoo, Arvine, Yao, Yong-Ming, Lu, Zhong-qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320320/
https://www.ncbi.nlm.nih.gov/pubmed/28270700
http://dx.doi.org/10.1155/2017/6848430

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