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Plasma from pre-pubertal obese children impairs insulin stimulated Nitric Oxide (NO) bioavailability in endothelial cells: Role of ER stress

Childhood obesity is commonly associated with early signs of endothelial dysfunction, characterized by impairment of insulin signaling and vascular Nitric Oxide (NO) availability. However, the underlying mechanisms remain to be established. Hence, we tested the hypothesis that endothelial insulin-st...

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Detalles Bibliográficos
Autores principales: Di Pietro, Natalia, Marcovecchio, M. Loredana, Di Silvestre, Sara, de Giorgis, Tommaso, Cordone, Vincenzo Giuseppe Pio, Lanuti, Paola, Chiarelli, Francesco, Bologna, Giuseppina, Mohn, Angelika, Pandolfi, Assunta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: North Holland Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320395/
https://www.ncbi.nlm.nih.gov/pubmed/28062198
http://dx.doi.org/10.1016/j.mce.2017.01.001