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Efficient mutagenesis by CRISPR/Cas system during meiotic maturation of porcine oocytes

Genome editing using the CRISPR/Cas system can induce mutations with high efficiency, and allows easier production of genome-modified animals than that offered by the conventional method where embryonic stem cells are used. However, studies using CRISPR/Cas systems have been mostly limited to prolif...

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Detalles Bibliográficos
Autores principales:	ONUMA, Asuka, FUJII, Wataru, SUGIURA, Koji, NAITO, Kunihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Society for Reproduction and Development 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320429/ https://www.ncbi.nlm.nih.gov/pubmed/27773884 http://dx.doi.org/10.1262/jrd.2016-094

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