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Metabolic profiling of presymptomatic Huntington’s disease sheep reveals novel biomarkers

The pronounced cachexia (unexplained wasting) seen in Huntington’s disease (HD) patients suggests that metabolic dysregulation plays a role in HD pathogenesis, although evidence of metabolic abnormalities in HD patients is inconsistent. We performed metabolic profiling of plasma from presymptomatic...

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Detalles Bibliográficos
Autores principales:	Skene, Debra J., Middleton, Benita, Fraser, Cara K., Pennings, Jeroen L. A., Kuchel, Timothy R., Rudiger, Skye R., Bawden, C. Simon, Morton, A. Jennifer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320451/ https://www.ncbi.nlm.nih.gov/pubmed/28223686 http://dx.doi.org/10.1038/srep43030

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