Targeted inhibition of Focal Adhesion Kinase Attenuates Cardiac Fibrosis and Preserves Heart Function in Adverse Cardiac Remodeling

Cardiac fibrosis in post-myocardial infarction (MI), seen in both infarcted and non-infarcted myocardium, is beneficial to the recovery of heart function. But progressively pathological fibrosis impairs ventricular function and leads to poor prognosis. FAK has recently received attention as a potent...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Fan, Guangpu, Zhao, Hui, Wang, Zhiwei, Li, Fei, Zhang, Peide, Zhang, Jing, Wang, Xu, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320468/
https://www.ncbi.nlm.nih.gov/pubmed/28225063
http://dx.doi.org/10.1038/srep43146

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