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Specific pathways mediating inflammasome activation by Candida parapsilosis

Candida albicans and C. parapsilosis are human pathogens causing severe infections. The NLRP3 inflammasome plays a crucial role in host defence against C. albicans, but it has been previously unknown whether C. parapsilosis activates this complex. Here we show that C. parapsilosis induces caspase-1...

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Detalles Bibliográficos
Autores principales: Tóth, Adél, Zajta, Erik, Csonka, Katalin, Vágvölgyi, Csaba, Netea, Mihai G., Gácser, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320503/
https://www.ncbi.nlm.nih.gov/pubmed/28225025
http://dx.doi.org/10.1038/srep43129