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Specific pathways mediating inflammasome activation by Candida parapsilosis

Candida albicans and C. parapsilosis are human pathogens causing severe infections. The NLRP3 inflammasome plays a crucial role in host defence against C. albicans, but it has been previously unknown whether C. parapsilosis activates this complex. Here we show that C. parapsilosis induces caspase-1...

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Detalles Bibliográficos
Autores principales:	Tóth, Adél, Zajta, Erik, Csonka, Katalin, Vágvölgyi, Csaba, Netea, Mihai G., Gácser, Attila
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320503/ https://www.ncbi.nlm.nih.gov/pubmed/28225025 http://dx.doi.org/10.1038/srep43129

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