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Rheb1 deletion in myeloid cells aggravates OVA-induced allergic inflammation in mice

The small GTPase ras homolog enriched in brain (Rheb) is a downstream target of tuberous sclerosis complex 1/2 (TSC1/2) and an upstream activator of the mechanistic target of rapamycin complex 1 (mTORC1), the emerging essential modulator of M1/M2 balance in macrophages. However, the role and regulat...

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Detalles Bibliográficos
Autores principales:	Li, Kai, Zhang, Yue, Liang, Kang Yan, Xu, Song, Zhou, Xue Juan, Tan, Kang, Lin, Jun, Bai, Xiao Chun, Yang, Cui Lan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320517/ https://www.ncbi.nlm.nih.gov/pubmed/28225024 http://dx.doi.org/10.1038/srep42655

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