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Large tandem chromosome expansions facilitate niche adaptation during persistent infection with drug-resistant Staphylococcus aureus

We used genomics to study the evolution of meticillin-resistant Staphylococcus aureus (MRSA) during a complex, protracted clinical infection. Preparing closed MRSA genomes from days 0 and 115 allowed us to precisely reconstruct all genetic changes that occurred. Twenty-three MRSA blood cultures were...

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Detalles Bibliográficos
Autores principales:	Gao, Wei, Monk, Ian R., Tobias, Nicholas J., Gladman, Simon L., Seemann, Torsten, Stinear, Timothy P., Howden, Benjamin P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for General Microbiology 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320569/ https://www.ncbi.nlm.nih.gov/pubmed/28348811 http://dx.doi.org/10.1099/mgen.0.000026

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