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epiG: statistical inference and profiling of DNA methylation from whole-genome bisulfite sequencing data

The study of epigenetic heterogeneity at the level of individual cells and in whole populations is the key to understanding cellular differentiation, organismal development, and the evolution of cancer. We develop a statistical method, epiG, to infer and differentiate between different epi-allelic h...

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Detalles Bibliográficos
Autores principales: Vincent, Martin, Mundbjerg, Kamilla, Skou Pedersen, Jakob, Liang, Gangning, Jones, Peter A., Ørntoft, Torben Falck, Dalsgaard Sørensen, Karina, Wiuf, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320668/
https://www.ncbi.nlm.nih.gov/pubmed/28222791
http://dx.doi.org/10.1186/s13059-017-1168-4

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