Synthetic curcumin derivative DK1 possessed G2/M arrest and induced apoptosis through accumulation of intracellular ROS in MCF-7 breast cancer cells

AIMS: Curcumin is a lead compound of the rhizomes of Curcuma longa and possess a broad range of pharmacological activities. Chemically, curcumin is 1,3-dicarbonyl class of compound, which exhibits keto-enol tautomerism. Despite of its strong biological properties, curcumin has yet been recommended a...

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Detalles Bibliográficos
Autores principales: Ali, Norlaily Mohd, Yeap, Swee Keong, Abu, Nadiah, Lim, Kian Lam, Ky, Huynh, Pauzi, Ahmad Zaim Mat, Ho, Wan Yong, Tan, Sheau Wei, Alan-Ong, Han Kiat, Zareen, Seema, Alitheen, Noorjahan Banu, Akhtar, M. Nadeem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320730/
https://www.ncbi.nlm.nih.gov/pubmed/28239299
http://dx.doi.org/10.1186/s12935-017-0400-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320730/
https://www.ncbi.nlm.nih.gov/pubmed/28239299
http://dx.doi.org/10.1186/s12935-017-0400-3

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