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Characterization of BRCA1 and BRCA2 variants in multi-ethnic Asian cohort from a Malaysian case-control study

BACKGROUND: Genetic testing for BRCA1 and BRCA2 has led to the accurate identification of individuals at higher risk of cancer and the development of new therapies. Approximately 10-20% of the genetic testing for BRCA1 and BRCA2 leads to the identification of variants of uncertain significance (VUS)...

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Detalles Bibliográficos
Autores principales:	Lai, Kah Nyin, Ho, Weang Kee, Kang, In Nee, Kang, Peter Choon Eng, Phuah, Sze Yee, Mariapun, Shivaani, Yip, Cheng-Har, Mohd Taib, Nur Aishah, Teo, Soo-Hwang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320733/ https://www.ncbi.nlm.nih.gov/pubmed/28222693 http://dx.doi.org/10.1186/s12885-017-3099-6

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