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Adult-to-adult living donor liver transplantation: Operative techniques to optimize the recipient's outcome

Adult-to-adult living donor liver transplantation (LDLT) is widely accepted today with good outcomes and safety reported worldwide for both donor and recipient. Nonetheless, it remained a highly demanding technical and complex surgery if undertaken. The last two decades have seen an increased in adu...

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Autores principales: Koh, Peng Soon, Chan, See Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320821/
https://www.ncbi.nlm.nih.gov/pubmed/28250667
http://dx.doi.org/10.4103/0976-9668.198356
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author Koh, Peng Soon
Chan, See Ching
author_facet Koh, Peng Soon
Chan, See Ching
author_sort Koh, Peng Soon
collection PubMed
description Adult-to-adult living donor liver transplantation (LDLT) is widely accepted today with good outcomes and safety reported worldwide for both donor and recipient. Nonetheless, it remained a highly demanding technical and complex surgery if undertaken. The last two decades have seen an increased in adult-to-adult LDLT following our first report of right lobe LDLT in overcoming graft size limitation in adults. In this article, we discussed the operative techniques and challenges of adult right lobe LDLT incorporating the middle hepatic vein, which is practiced in our center for the recipient operation. The various issues and challenges faced by the transplant surgeon in ensuring good recipient outcome are explored and discussed here as well. Hence, it is important to understand that a successful recipient operation is dependent of multifactorial events starting at the preoperative stage of planning, understanding the intraoperative technical challenges and the physiology of flow modulation that goes hand-in-hand with the operation. Therefore, one needs to arm oneself with all the possible knowledge in overcoming these technical challenges and the ability to be flexible and adaptable during LDLT by tailoring the needs of each patient individually.
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spelling pubmed-53208212017-03-01 Adult-to-adult living donor liver transplantation: Operative techniques to optimize the recipient's outcome Koh, Peng Soon Chan, See Ching J Nat Sci Biol Med Review Article Adult-to-adult living donor liver transplantation (LDLT) is widely accepted today with good outcomes and safety reported worldwide for both donor and recipient. Nonetheless, it remained a highly demanding technical and complex surgery if undertaken. The last two decades have seen an increased in adult-to-adult LDLT following our first report of right lobe LDLT in overcoming graft size limitation in adults. In this article, we discussed the operative techniques and challenges of adult right lobe LDLT incorporating the middle hepatic vein, which is practiced in our center for the recipient operation. The various issues and challenges faced by the transplant surgeon in ensuring good recipient outcome are explored and discussed here as well. Hence, it is important to understand that a successful recipient operation is dependent of multifactorial events starting at the preoperative stage of planning, understanding the intraoperative technical challenges and the physiology of flow modulation that goes hand-in-hand with the operation. Therefore, one needs to arm oneself with all the possible knowledge in overcoming these technical challenges and the ability to be flexible and adaptable during LDLT by tailoring the needs of each patient individually. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5320821/ /pubmed/28250667 http://dx.doi.org/10.4103/0976-9668.198356 Text en Copyright: © 2017 Journal of Natural Science, Biology and Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Review Article
Koh, Peng Soon
Chan, See Ching
Adult-to-adult living donor liver transplantation: Operative techniques to optimize the recipient's outcome
title Adult-to-adult living donor liver transplantation: Operative techniques to optimize the recipient's outcome
title_full Adult-to-adult living donor liver transplantation: Operative techniques to optimize the recipient's outcome
title_fullStr Adult-to-adult living donor liver transplantation: Operative techniques to optimize the recipient's outcome
title_full_unstemmed Adult-to-adult living donor liver transplantation: Operative techniques to optimize the recipient's outcome
title_short Adult-to-adult living donor liver transplantation: Operative techniques to optimize the recipient's outcome
title_sort adult-to-adult living donor liver transplantation: operative techniques to optimize the recipient's outcome
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320821/
https://www.ncbi.nlm.nih.gov/pubmed/28250667
http://dx.doi.org/10.4103/0976-9668.198356
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